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(247) demonstrated that Bifidobacterium strains effectively restore immune homeostasis in colitis models by upregulating regulatory T cell populations, which directly correlates with reduced tissue damage

10.1186/s12964-016-0158-628057038 320 Yan M, Chen K, He L, et al

The investigators concluded that all tested doses were tolerated and dose-dependently reduced body weight, explicitly framing the result as a rationale for further study